BDBM674540 ((3R,5R)-3-amino-5- fluoropiperidin-1-yl)(2- (4- (cyclopropylmethyl)-2- methyl-4H-thieno[3,2- b]pyrrol-5-yl)-7- methoxy-1-methyl-1H- benzo[d]imidazol-5- yl)methanone::US11981680, Example 28

SMILES COc1cc(cc2nc(-c3cc4sc(C)cc4n3CC3CC3)n(C)c12)C(=O)N1C[C@H](N)C[C@@H](F)C1

InChI Key InChIKey=ZAKAHILPOZRHQU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674540   

TargetProtein-arginine deiminase type-4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM674540(((3R,5R)-3-amino-5- fluoropiperidin-1-yl)(2- (4- (...)
Affinity DataIC50: 67nMAssay Description:Compounds were solubilized in 100% DMSO to achieve a10 mM compound concentration. Compound stock solutions were stored at RT. A series of dilutions w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent