BDBM674657 US20240158368, Compound 4

SMILES Fc1cccc2c(cc(=O)[nH]c12)C(=O)N[C@H]1CCN(C1)c1c(cc(cc1C(F)(F)F)C#N)C(=O)N1CCOCC1

InChI Key

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 674657   

TargetReplicase polyprotein 1ab(2019-nCoV)
Abbvie

US Patent
LigandPNGBDBM674657(US20240158368, Compound 4)
Affinity DataEC50:  8.72nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
Abbvie

US Patent
LigandPNGBDBM674657(US20240158368, Compound 4)
Affinity DataEC50:  9.93nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Abbvie

US Patent
LigandPNGBDBM674657(US20240158368, Compound 4)
Affinity DataEC50:  39.8nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetReplicase polyprotein 1ab(HCoV-OC43)
Abbvie

US Patent
LigandPNGBDBM674657(US20240158368, Compound 4)
Affinity DataEC50:  241nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetOrf1a protein(MERS-CoV)
Abbvie

US Patent
LigandPNGBDBM674657(US20240158368, Compound 4)
Affinity DataEC50:  12.3nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent