BDBM674713 US20240158368, Compound 60

SMILES Cc1cc(C2CC2)c(N2CC[C@H](C2)NC(=O)c2cc(C)[nH]c(=O)c2F)c(c1)C(=O)N1CCOCC1

InChI Key InChIKey=YEZLDKFEFHWTAJ-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 674713   

TargetReplicase polyprotein 1ab(2019-nCoV)
Abbvie

US Patent
LigandPNGBDBM674713(US20240158368, Compound 60)
Affinity DataEC50:  0.480nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
Abbvie

US Patent
LigandPNGBDBM674713(US20240158368, Compound 60)
Affinity DataEC50:  0.740nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-OC43)
Abbvie

US Patent
LigandPNGBDBM674713(US20240158368, Compound 60)
Affinity DataEC50:  1.22nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Abbvie

US Patent
LigandPNGBDBM674713(US20240158368, Compound 60)
Affinity DataEC50:  1.40nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Abbvie

US Patent
LigandPNGBDBM674713(US20240158368, Compound 60)
Affinity DataEC50:  5.14nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent