BDBM674999 1-(5-(4-amino-7-cyclopropyl- 7H-pyrrolo[2,3-d]pyrimidin- 5-yl)imidazo[1,2-a]pyridin-8- yl)-3-(5-(tert-butyl)isoxazol-3- yl)urea::US20240158394, Compound I-27

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn(C4CC4)c4ncnc(N)c34)n3ccnc23)no1

InChI Key InChIKey=IIFAATJJRIUKME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674999   

TargetSerine/threonine-protein kinase Nek7(Human)
Halia Therapeutics

US Patent
LigandPNGBDBM674999(1-(5-(4-amino-7-cyclopropyl- 7H-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 200nMAssay Description:Casein substrate (from bovine milk, hydrolyzed and partially dephosphorylated mixture of α, β and κ caseins, obtained from Sigma Aldri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent