BDBM675039 1-(7-(4-amino-7-cyclopropyl- 7H-pyrrolo[2,3-d]pyrimidin- 5-yl)benzo[c][1,2,5]oxadiazol- 4-yl)-3-(4-((1-methylpiperidin- 4-yl)oxy)-3-(trifluoromethyl)- phenyl)urea::US20240158394, Compound I-79

SMILES CN1CCC(CC1)Oc1ccc(NC(=O)Nc2ccc(-c3cn(C4CC4)c4ncnc(N)c34)c3nonc23)cc1C(F)(F)F

InChI Key InChIKey=ZRYKQTGBSDDNKX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 675039   

TargetSerine/threonine-protein kinase Nek7(Human)
Halia Therapeutics

US Patent
LigandPNGBDBM675039(1-(7-(4-amino-7-cyclopropyl- 7H-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 200nMAssay Description:Casein substrate (from bovine milk, hydrolyzed and partially dephosphorylated mixture of α, β and κ caseins, obtained from Sigma Aldri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent