BDBM675045 1-(5-(4-amino-7-(2-methoxy- ethyl)-7H-pyrrolo[2,3-d]- pyrimidin-5-yl)imidazo[1,2- a]pyridin-8-yl)-3-(5-(1- (trifluoromethyl)cyclopropyl)- isoxazol-3-yl)urea::US20240158394, Compound I-89

SMILES COCCn1cc(-c2ccc(NC(=O)Nc3cc(on3)C3(CC3)C(F)(F)F)c3nccn23)c2c(N)ncnc12

InChI Key InChIKey=XKUZOKSCCCXQPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 675045   

TargetSerine/threonine-protein kinase Nek7(Human)
Halia Therapeutics

US Patent
LigandPNGBDBM675045(1-(5-(4-amino-7-(2-methoxy- ethyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 200nMAssay Description:Casein substrate (from bovine milk, hydrolyzed and partially dephosphorylated mixture of α, β and κ caseins, obtained from Sigma Aldri...More data for this Ligand-Target Pair
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Date in BDB:
8/19/2024
Entry Details
US Patent