BDBM675061 1-(5-(4-amino-7-(2-hydroxy-2- methylpropyl)-7H-pyrrolo[2,3- d]pyrimidin-5-yl)imidazo[1,2- a]pyridin-8-yl)-3-(4-((4-meth- ylpiperazin-1-yl)methyl)-3- (trifluoromethyl)phenyl)urea::US20240158394, Compound I-131

SMILES CN1CCN(Cc2ccc(NC(=O)Nc3ccc(-c4cn(CC(C)(C)O)c5ncnc(N)c45)n4ccnc34)cc2C(F)(F)F)CC1

InChI Key InChIKey=LFKGLFRMFUZAST-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 675061   

TargetSerine/threonine-protein kinase Nek7(Human)
Halia Therapeutics

US Patent
LigandPNGBDBM675061(1-(5-(4-amino-7-(2-hydroxy-2- methylpropyl)-7H-pyr...)
Affinity DataIC50: 200nMAssay Description:Casein substrate (from bovine milk, hydrolyzed and partially dephosphorylated mixture of α, β and κ caseins, obtained from Sigma Aldri...More data for this Ligand-Target Pair
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Date in BDB:
8/19/2024
Entry Details
US Patent