BDBM675344 US20240158414, Example 101

SMILES CC(Oc1cc(c(F)cc1C(=O)Nc1c(C)n[nH]c1C(F)(F)F)-c1cnc(C)c(CO)n1)C(F)(F)F

InChI Key InChIKey=NAASDWBHYGJPKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 675344   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Biotech

US Patent
LigandPNGBDBM675344(US20240158414, Example 101)
Affinity DataIC50: 0.170nMAssay Description:DHODH Enzymatic Assay: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent