BDBM676762 (R)-6-(3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-::US20240166651, Example 3

SMILES CN(c1ncnc2[nH]ccc12)[C@@H]1CCN(c2ccc(C(=O)Nc3nccs3)cn2)C1

InChI Key InChIKey=FOXVOESWDFDFDJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 676762   

TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandChemical structure of BindingDB Monomer ID 676762BDBM676762((R)-6-(3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4- | U...)
Affinity DataIC50: 20nMAssay Description:The objective of this study was to assess the activity of novel JAK inhibitors measuring the capability of compounds to inhibit JAK1 kinase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent