BDBM676896 US20240166660, Compound B93

SMILES CO[C@@H]1CC(COc2nc(N3CCN([C@@H](CC#N)C3)C(=O)C(F)=C)c3c4OCCCc4c(cc3n2)-c2cccc3cccc(Cl)c23)N(C)C1

InChI Key InChIKey=QTHZQQUEYHZQIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 676896   

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM676896(US20240166660, Compound B93)
Affinity DataIC50: 11nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent