BDBM676897 US20240166660, Compound B106::US20240166660, Compound B107::US20240166660, Compound B94::US20240166660, Compound B95
SMILES CO[C@@H]1C[C@H](COc2nc(N3CCN([C@@H](CC#N)C3)C(=O)C(F)=C)c3c4OCCCc4c(cc3n2)-c2cccc3cccc(Cl)c23)N(C)C1
InChI Key InChIKey=QTHZQQUEYHZQIP-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 676897
Affinity DataIC50: 3.26nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.63nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.54nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
Affinity DataIC50: 11.5nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair