BDBM677104 Synthesis of N2-(6-fluoro-1H-indazol-4-yl)-N4-methyl-5-(trifluoromethyl)pyrimidine-2,4-diamine::US20240174647, Example 25

SMILES CNc1nc(Nc2cc(F)cc3[nH]ncc23)ncc1C(F)(F)F

InChI Key InChIKey=RPJHQKUNGXHGGB-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677104   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Neuron23

US Patent

LigandBDBM677104(Synthesis of N2-(6-fluoro-1H-indazol-4-yl)-N4-meth...)Copy SMILESCopy InChI

Affinity DataIC50: <50nMAssay Description:The protocol for basic TR-FRET LanthaScreen Tb Kinase Activity Assay inhibitor studies were as follows. LanthaScreen Kinase Activity Assays (ThermoFi...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent

Copy BDB DOI
Copy reaction URL