BDBM677481 US20240174662, Example 145

SMILES CCc1cc(Nc2cc3cc(ccn3n2)-c2c(OC[C@H]3CCN3C)cnn2C)nc(C)n1

InChI Key InChIKey=LAOKKTVNXHXUKB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677481   

TargetSerine/threonine-protein kinase SIK2(Human)
Janssen Biotech

US Patent
LigandPNGBDBM677481(US20240174662, Example 145)
Affinity DataIC50: 0.847nMAssay Description:All steps were performed at room temperature. Compounds were pre-plated onto an assay plate using an Echo acoustic dispenser (Labcyte, E550 or E555) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent