BDBM677949 US20240174674, Compound 293

SMILES O[C@@H]1CN(CC[C@@H]1NC(=O)c1cc(F)ccc1Cl)c1ccc(cn1)-c1cc(OCC(F)F)cn2nc3[nH]ncc3c12

InChI Key InChIKey=WYVCRYUWCKTYJL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677949   

TargetProto-oncogene tyrosine-protein kinase receptor Ret [G810R](Human)
Applied Pharmaceutical Science

US Patent
LigandPNGBDBM677949(US20240174674, Compound 293)
Affinity DataIC50: 1.60nMAssay Description:a) 10 nL of compound dilution was transferred to each well of the test plate;b) the compound plate was centrifuged at 1000 g for 1 min;c) the test pl...More data for this Ligand-Target Pair
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Date in BDB:
9/5/2024
Entry Details
US Patent