BDBM678367 US20240174692, Compound 004

SMILES Nc1nc2c(ccc(F)c2s1)-c1c(Cl)cc2c(nc(OCC34CCCN3C[C@H](F)C4)nc2c1F)N1CC2CCC(C1)N2

InChI Key InChIKey=SDXLEIDIYQSYQN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 678367   

TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM678367(US20240174692, Compound 004)
Affinity DataIC50: 0.5nMAssay Description:1) KRAS Nucleotide Exchange Buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent