BDBM679180 US11999676, Compound 115::US11999676, Compound 116::US11999676, Compound 42

SMILES CC(Cc1ccc(cc1)[N+]([O-])=O)NCCCc1ccccc1

InChI Key InChIKey=YDKSREDJZJHEJY-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 679180   

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM679180(US11999676, Compound 42 | US11999676, Compound 115...)
Affinity DataKi:  13nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM679180(US11999676, Compound 42 | US11999676, Compound 115...)
Affinity DataKi:  19nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM679180(US11999676, Compound 42 | US11999676, Compound 115...)
Affinity DataKi:  19nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM679180(US11999676, Compound 42 | US11999676, Compound 115...)
Affinity DataKi:  285nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM679180(US11999676, Compound 42 | US11999676, Compound 115...)
Affinity DataKi:  285nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM679180(US11999676, Compound 42 | US11999676, Compound 115...)
Affinity DataKi:  2.00E+3nMAssay Description:Synaptic vesicles were prepared from rat brain using a modification of a previously described procedure (Teng et al., 1998). Briefly, fresh whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent