BDBM679197 US11999676, Compound 59

SMILES CC(Cc1ccc(F)c(F)c1)NCCCc1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=JMIQPGAOENFTJZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 679197   

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM679197(US11999676, Compound 59)
Affinity DataKi:  13.1nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM679197(US11999676, Compound 59)
Affinity DataKi:  55.6nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent