BDBM679434 6-((4-(1,1-dioxido-4- oxo-1,2,5- thiadiazolidin-2-yl)-3- fluoro-5- hydroxybenzyl) amino)-4- methylnicotinonitrile::US20240180886, Example 32

SMILES Cc1cc(NCc2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2)ncc1C#N

InChI Key InChIKey=WWCUBVNKPWAVON-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 679434   

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM679434(US20240180886, Example 32 | 6-((4-(1,1-dioxido-4- ...)
Affinity DataIC50: 30nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM679434(US20240180886, Example 32 | 6-((4-(1,1-dioxido-4- ...)
Affinity DataIC50: 50nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent