BDBM679448 5-(4-(((4- (benzyloxy)pyridin-2- yl)amino)methyl)-2- fluoro-6- hydroxyphenyl)-1,2,5- thiadiazolidin-3-one 1,1-dioxide::US20240180886, Example 46

SMILES Oc1cc(CNc2cc(OCc3ccccc3)ccn2)cc(F)c1N1CC(=O)NS1(=O)=O

InChI Key InChIKey=JKWGDMFTVJHDAG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 679448   

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM679448(US20240180886, Example 46 | 5-(4-(((4- (benzyloxy)...)
Affinity DataIC50: 6nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM679448(US20240180886, Example 46 | 5-(4-(((4- (benzyloxy)...)
Affinity DataIC50: 10nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent