BDBM679460 1-(9-chloro-2,3-dimethoxy-5,6,8,9,10,11-hexahydro-7H-5,9:7,11-dimethanobenzo[9]annulen-7-yl)-3-(1-(tetrahydro-2H-pyran-4-carbonyl)piperidin-4-yl)urea::US20240182406, Example 6

SMILES COc1cc2C3CC4(Cl)CC(CC(C3)(C4)NC(=O)NC3CCN(CC3)C(=O)C3CCOCC3)c2cc1OC

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 679460   

TargetEpoxide hydrolase 1(Human)
Universitat De Barcelona

US Patent
LigandPNGBDBM679460(1-(9-chloro-2,3-dimethoxy-5,6,8,9,10,11-hexahydro-...)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
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Date in BDB:
9/18/2024
Entry Details
US Patent