BDBM679517 US20240182453, Example 44

SMILES Cc1cnc(cn1)C(=O)N[C@@H](C1CC1)c1nc2c(C)c(ccc2n1CC(F)F)C#N

InChI Key InChIKey=UCAANBVNCBVXCC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 679517   

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM679517(US20240182453, Example 44 | US12421218, Example 44)
Affinity DataIC50: 5nMAssay Description:The cAMP standard is prepared by diluting the cAMP stock solution with HBSS/Hepes buffer: 5 μl/well of the cAMP dilutions (in HBSS/Hepes buffer conta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2026
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM679517(US20240182453, Example 44 | US12421218, Example 44)
Affinity DataIC50: 5nMAssay Description:The in vitro activity of the compounds according to the invention may be investigated as follows:[0111]The HEK293 cell overexpressing the human metab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent