BDBM679716 (12S,14S)-11-((5-methoxy-7-methyl-1H-indol- 4-yl)methyl)-N-(methylsulfonyl)-3,10-dioxa- 1(2,4)-piperidina-2(1,2)- benzenacyclodecaphane-24-carboxamide::US20240182503, Example 33

SMILES COc1cc(C)c2[nH]ccc2c1CN1CC[C@H]2C[C@H]1c1ccc(cc1OCCCCCCO2)C(=O)NS(C)(=O)=O

InChI Key InChIKey=CUMTXPQXTNWXLN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 679716   

TargetComplement Factor B/Cobra Venom Factor(Monocled cobra)
Alexion Pharmaceuticals

US Patent
LigandPNGBDBM679716((12S,14S)-11-((5-methoxy-7-methyl-1H-indol- 4-yl)m...)
Affinity DataIC50: 96nMAssay Description:CVF-Bb complex, prepared from purified cobra venom factor, (3 nM) is incubated with a compound of the disclosure at various concentrations for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent