BDBM679725 (12R,14R)-11-((5-methoxy-7-methyl-1H-indol- 4-yl) methyl)-11-oxa-1(2,4)-piperidina-2(1,2)- benzenacycloundecaphane-24-carboxylic acid::US20240182503, Example 41

SMILES COc1cc(C)c2[nH]ccc2c1CN1CC[C@H]2C[C@H]1c1ccc(cc1CCCCCCCCO2)C(O)=O

InChI Key InChIKey=NEXAZZZDHNPLGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 679725   

TargetComplement Factor B/Cobra Venom Factor(Monocled cobra)
Alexion Pharmaceuticals

US Patent
LigandPNGBDBM679725((12R,14R)-11-((5-methoxy-7-methyl-1H-indol- 4-yl) ...)
Affinity DataIC50: 129nMAssay Description:CVF-Bb complex, prepared from purified cobra venom factor, (3 nM) is incubated with a compound of the disclosure at various concentrations for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent