BDBM679726 (12R,14R,Z)-11-((5-methoxy-7-methyl-1H- indol-4-yl)methyl)-3,9-dioxa-1(2,4)-piperidina- 2(1,2)-benzenacyclononaphan-6-ene-24- carboxylic acid::US20240182503, Example 42

SMILES COc1cc(C)c2[nH]ccc2c1CN1CC[C@@H]2C[C@@H]1c1ccc(cc1OCC\C=C/CO2)C(O)=O

InChI Key InChIKey=KCDGLGUJXVORKM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 679726   

TargetComplement Factor B/Cobra Venom Factor(Monocled cobra)
Alexion Pharmaceuticals

US Patent
LigandPNGBDBM679726((12R,14R,Z)-11-((5-methoxy-7-methyl-1H- indol-4-yl...)
Affinity DataIC50: 1.06E+3nMAssay Description:CVF-Bb complex, prepared from purified cobra venom factor, (3 nM) is incubated with a compound of the disclosure at various concentrations for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent