BDBM679728 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl- 1H-indol-4-yl)methyl)piperidin-2-yl)-N- (ethylsulfonyl)benzamide::US20240182503, Example 44

SMILES CCO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)C(C1)c1ccc(cc1)C(=O)NS(=O)(=O)CC

InChI Key InChIKey=GIGRJLPBMNDKQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 679728   

TargetComplement Factor B/Cobra Venom Factor(Monocled cobra)
Alexion Pharmaceuticals

US Patent
LigandPNGBDBM679728(4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl- 1H-ind...)
Affinity DataIC50: 138nMAssay Description:CVF-Bb complex, prepared from purified cobra venom factor, (3 nM) is incubated with a compound of the disclosure at various concentrations for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent