BDBM679729 (12S,14S)-N-(ethylsulfonyl)-11-((5-methoxy-7- methyl-1H-indol-4-yl)methyl)-3,10-dioxa- 1(2,4)-piperidina-2(1,2)- benzenacyclodecaphane-24-carboxamide::US20240182503, Example 45

SMILES CCS(=O)(=O)NC(=O)c1ccc2[C@@H]3C[C@H](CCN3Cc3c(OC)cc(C)c4[nH]ccc34)OCCCCCCOc2c1

InChI Key InChIKey=IKVHQQQXCFVEKL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 679729   

TargetComplement Factor B/Cobra Venom Factor(Monocled cobra)
Alexion Pharmaceuticals

US Patent
LigandPNGBDBM679729((12S,14S)-N-(ethylsulfonyl)-11-((5-methoxy-7- meth...)
Affinity DataIC50: 396nMAssay Description:CVF-Bb complex, prepared from purified cobra venom factor, (3 nM) is incubated with a compound of the disclosure at various concentrations for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent