BDBM679733 (12S,14S,E)-11-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)-3,10-dioxa-1(2,4)-piperidina-2(1,7)-naphthalenacyclodecaphan-7-ene-24-carboxylic acid and (12S,14S)-11-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)-3,10-dioxa-1(2,4)-piperidina-2(1,7)-naphthalenacyclodecaphane-24-carboxylic acid::US20240182503, Example 49

SMILES COc1cc(C)c2[nH]ccc2c1CN1CC[C@H]2C[C@H]1c1ccc(C(O)=O)c3ccc(OCCCCCCO2)cc13

InChI Key InChIKey=CUODNUZQJUANQR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 679733   

TargetComplement Factor B/Cobra Venom Factor(Monocled cobra)
Alexion Pharmaceuticals

US Patent
LigandPNGBDBM679733((12S,14S,E)-11-((5-methoxy-7-methyl-1H-indol-4-yl)...)
Affinity DataIC50: 208nMAssay Description:CVF-Bb complex, prepared from purified cobra venom factor, (3 nM) is incubated with a compound of the disclosure at various concentrations for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent