BDBM680587 5-{6-[2-(2-Cyano-7-fluoro-4-methoxy-indol-1-yl)-ethylamino]-pyrimidin-4-yl}-3-isopropoxy-thiophene-2-carboxylic acid::US12011444, Example 802

SMILES COc1ccc(F)c2n(CCNc3cc(ncn3)-c3cc(OC(C)C)c(s3)C(O)=O)c(cc12)C#N

InChI Key InChIKey=QJSNBTYXZIFGID-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 680587   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680587(US12011444, Example 802 | 5-{6-[2-(2-Cyano-7-fluor...)
Affinity DataIC50: 1nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680587(US12011444, Example 802 | 5-{6-[2-(2-Cyano-7-fluor...)
Affinity DataIC50: 7nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent