BDBM680604 7-Fluoro-4-methoxy-1-(2-{6-[4-(5-methyl-1H-imidazol-4-yl)-phenyl]-pyrimidin-4- ylamino}-ethyl)-1H-indole-2-carbonitrile::US12011444, Example 819

SMILES COc1ccc(F)c2n(CCNc3cc(ncn3)-c3ccc(cc3)-c3nc[nH]c3C)c(cc12)C#N

InChI Key InChIKey=ZBQSVKKAFFYMHA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 680604   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680604(US12011444, Example 819 | 7-Fluoro-4-methoxy-1-(2-...)
Affinity DataIC50: 2nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680604(US12011444, Example 819 | 7-Fluoro-4-methoxy-1-(2-...)
Affinity DataIC50: 7nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent