BDBM680605 1-(2-{6-[3-Ethoxy-4-(5-oxo-4,5-dihydro-[1,2,4]oxadiazol-3-yl)-phenyl]-pyrimidin-4-ylamino}-ethyl)-7-fluoro-4-methoxy-1H-indole-2-carbonitrile::US12011444, Example 820

SMILES CCOc1cc(ccc1-c1noc(=O)[nH]1)-c1cc(NCCn2c(cc3c(OC)ccc(F)c23)C#N)ncn1

InChI Key InChIKey=CEGDFWJMNQOQCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 680605   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680605(US12011444, Example 820 | 1-(2-{6-[3-Ethoxy-4-(5-o...)
Affinity DataIC50: 2nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680605(US12011444, Example 820 | 1-(2-{6-[3-Ethoxy-4-(5-o...)
Affinity DataIC50: 6nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent