BDBM681588 US20240199605, Example 147

SMILES CN1CC[C@@](O)(C#Cc2cccc(c2)-c2ncc3c(cnc(N)c3n2)-c2ccc(nc2)C(F)(F)F)C1=O

InChI Key InChIKey=WWMBWXNMQIOWQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 681588   

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM681588(US20240199605, Example 147)
Affinity DataIC50: 0.5nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (alphascreen) format (Perkin Elmer). All compounds tested were dissolved...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
US Patent