BDBM682238 US20240207267, Example 7

SMILES OC[C@@H]1CCN(C1)c1cc(F)c([C@H]2CCC(=O)NC2=O)c(F)c1

InChI Key InChIKey=MWJKFQNOTIMGAR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682238   

TargetDNA damage-binding protein 1/Protein Cereblon [40-442](Homo sapiens (Human))
Beigene Switzerland

US Patent
LigandPNGBDBM682238(US20240207267, Example 7)
Affinity DataIC50: 22nMAssay Description:Biochemical potency of compound was determined by using CRBN& DDB1 protein (His Tag). Compounds were tested for blocking the binding of CRBN&DDB1 pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent