BDBM682243 3-(4-(2-hydroxyethyl)phenyl)piperidine-2,6-dione::US20240207267, Example 15

SMILES OCCc1ccc(cc1)C1CCC(=O)NC1=O

InChI Key InChIKey=TYKAMJNGHVMWDX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682243   

TargetDNA damage-binding protein 1/Protein Cereblon [40-442](Homo sapiens (Human))
Beigene Switzerland

US Patent
LigandPNGBDBM682243(US20240207267, Example 15 | 3-(4-(2-hydroxyethyl)p...)
Affinity DataIC50: 239nMAssay Description:Biochemical potency of compound was determined by using CRBN& DDB1 protein (His Tag). Compounds were tested for blocking the binding of CRBN&DDB1 pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent