BDBM682273 DOTA[(Gd(III)]- HyBz-D-Ala- boroPro::US20240207292, Compound 5183

SMILES C[C@@H](NC(=O)c1ccc(NNC(=O)CN2CCN3CC(=O)OC4(CN5CCN6CC(=O)OC(C2)(C6)[Gd]4OC(=O)C5)C3)cc1)C(=O)N1CCC[C@H]1B(O)O

InChI Key InChIKey=ZAARZJZAJFNJOU-UHFFFAOYSA-M

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 682273   

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandChemical structure of BindingDB Monomer ID 682273BDBM682273(US20240207292, Compound 5183 | DOTA[(Gd(III)]- HyB...)
Affinity DataIC50: 5.30nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandChemical structure of BindingDB Monomer ID 682273BDBM682273(US20240207292, Compound 5183 | DOTA[(Gd(III)]- HyB...)
Affinity DataIC50: 68nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetPresequence protease, mitochondrial(Human)
Tufts College

US Patent
LigandChemical structure of BindingDB Monomer ID 682273BDBM682273(US20240207292, Compound 5183 | DOTA[(Gd(III)]- HyB...)
Affinity DataIC50: 910nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent