BDBM682721 US20240208945, Compound 16

SMILES COc1cc2nc(C)nc(N[C@H](C)c3cccc(c3)C(F)(F)CO)c2cc1OC(=O)N1CCN(C)CC1C

InChI Key InChIKey=YKWQHXRKTCHHTQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682721   

TargetSon of sevenless homolog 1 [564-1049]/GTPase KRas [G12C](Human)
Medshine Discovery

US Patent
LigandPNGBDBM682721(US20240208945, Compound 16)
Affinity DataIC50: 59.6nMAssay Description:1× buffer preparation (ready-to-use): Hepes: 5 mM; NaCl: 150 mM; EDTA: 10 mM; Igepal: 0.0025%; KF: 100 mM; DTT: 1 mM; BSA: 005%;The test compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent