BDBM682735 8-fluoro-6-((R)-2-((3aR,5R,6aS)-5-(2-fluorophenoxy)-3a-hydroxyhexahydrocyclopenta[c]pyrrol-2(1H)-yl)-1-hydroxyethyl)-3,4-dihydroquinolin-2(1H)-one::US20240208953, Example 6C

SMILES O[C@H](CN1C[C@@H]2C[C@H](C[C@]2(O)C1)Oc1ccccc1F)c1cc(F)c2NC(=O)CCc2c1

InChI Key InChIKey=BGTFYUBZBJUYMY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682735   

LigandPNGBDBM682735(US20240208953, Example 6C | 8-fluoro-6-((R)-2-((3a...)
Affinity DataIC50: 1.33E+4nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent