BDBM682738 US20240208953, Example 10A

SMILES O[C@@H](CN1C[C@H]2C[C@@H](C[C@@]2(O)C1)Oc1ccccc1)c1cc2CCC(=O)Nc2cc1F

InChI Key InChIKey=GTGMRXKOGVFJHY-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682738   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis

US Patent

LigandBDBM682738(US20240208953, Example 10A)Copy SMILESCopy InChI

Affinity DataIC50: 2.10E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/4/2024
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL