BDBM682746 6-((R)-1-hydroxy-2-((3aS,5S,6aR)-3a-hydroxy-5-phenoxyhexahydrocyclopenta[c]pyrrol-2(1H)-yl)ethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one::US20240208953, Example 28A::US20240208953, Example 33A

SMILES O[C@@H](CN1C[C@H]2C[C@@H](C[C@@]2(O)C1)Oc1ccccc1)c1cc(F)c2NC(=O)OCc2c1

InChI Key InChIKey=ZDLQYKAWFDAUJP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 682746   

LigandPNGBDBM682746(US20240208953, Example 28A | 6-((R)-1-hydroxy-2-((...)
Affinity DataIC50: 2.40E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandPNGBDBM682746(US20240208953, Example 28A | 6-((R)-1-hydroxy-2-((...)
Affinity DataIC50: 8.20E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent