BDBM682754 US20240208953, Example 42B

SMILES O[C@H](CN1C[C@H]2C[C@@H](C[C@@]2(O)C1)Oc1ccccc1)c1cc(F)c2[nH]c(=O)sc2c1

InChI Key InChIKey=NCSDFUPKIIXKHF-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682754   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis

US Patent

LigandBDBM682754(US20240208953, Example 42B)Copy SMILESCopy InChI

Affinity DataIC50: 800nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/4/2024
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL