BDBM682832 7-(isoquinolin-4-yl)-2- methyl-2-phenyl- 5,7- diazaspiro[3.4]octane- 6,8-dione::US20240208970, Compound 39

SMILES CC2(c1ccccc1)CC5(C2)NC(=O)N(c3cncc4ccccc34)C5=O

InChI Key InChIKey=OTGCKDLPVNKYIH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682832   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 682832BDBM682832(US20240208970, Compound 39 | 7-(isoquinolin-4-yl)-...)
Affinity DataIC50: 71nMAssay Description:Inhibition of SARS-CoV-2 Main protease assessed as hydrolysis of quenched fluorogenic substrateMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed