BDBM682903 (2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl)((3R,6S)-5-(6-(2-hydroxypropan-2-yl)-4-methylpyridin-2-yl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)methanone::US20240208981, Compound 60

SMILES Cc1cc(nc(c1)C(C)(C)O)N1C[C@@H]2CN(C[C@@H]2C1)C(=O)c1c(F)cccc1-n1nccn1

InChI Key InChIKey=GUTZEJYDVLRLLR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682903   

TargetCytochrome P450 1A2(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM682903(US20240208981, Compound 60 | (2-fluoro-6-(2H-1,2,3...)
Affinity DataIC50: 1.00E+5nMAssay Description:1. Experimental ObjectiveThe human liver microsome incubation system was used to rapidly predict the inhibitory effect of the compounds on CYP450 enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent