BDBM682964 US20240208986, Compound 1-55::methyl 4-[(2S,5S)-2,3- dihydro-2,5-methano-1,4- benzoxazepine-4(5H)- carbonyl]bicyclo[2.2.1] heptane-1-carboxylate

SMILES COC(=O)C12CCC(CC1)(C2)C(=O)N1C[C@@H]2C[C@H]1c1ccccc1O2

InChI Key InChIKey=VGRCBCPBBNEOCG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682964   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM682964(US20240208986, Compound 1-55 | methyl 4-[(2S,5S)-2...)
Affinity DataIC50: 43nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent