BDBM682975 1-[(2S,5S)-9-fluoro-2,3- dihydro-2,5-methano-1,4- benzoxazepin-4(5H)-yl]- 2,2-dimethylpropan-1-one::US20240208986, Compound 2-6

SMILES CC(C)(C)C(=O)N1C[C@@H]2C[C@H]1c1cccc(F)c1O2

InChI Key InChIKey=RJCOBWLZDIKXRA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682975   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM682975(US20240208986, Compound 2-6 | 1-[(2S,5S)-9-fluoro-...)
Affinity DataIC50: 43nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent