BDBM682988 (2S,5S)-4-(3,3-difluoro- 2,2-dimethylpropanoyl)- 2,3,4,5-tetrahydro-2,5- methano-1,4- benzoxazepine-9- carbonitrile::US20240208986, Compound 2-19

SMILES CC(C)(C(F)F)C(=O)N1C[C@@H]2C[C@H]1c1cccc(C#N)c1O2

InChI Key InChIKey=AUYGCSQNZQRFNX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682988   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM682988(US20240208986, Compound 2-19 | (2S,5S)-4-(3,3-difl...)
Affinity DataIC50: 18nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent