BDBM683004 ((2S,5S)-7,9-difluoro-2,3- dihydro-2,5- methanobenzo[f][1,4]oxaze- pin-4(5H)-yl)(4- fluorobicyclo[2.2.1]heptan- 1-yl)methanone::US20240208986, Compound 2-35

SMILES Fc1cc(F)c2O[C@H]3C[C@H](N(C3)C(=O)C34CCC(F)(CC3)C4)c2c1

InChI Key InChIKey=NREMFFSMOIGPTO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683004   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM683004(US20240208986, Compound 2-35 | ((2S,5S)-7,9-difluo...)
Affinity DataIC50: 12nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent