BDBM683180 4-(5-(4- aminopiperidin-1- yl)-8-(3-hydroxy- 4-(trifluoromethoxy) phenyl)imidazolo [1,2-c]pyrimidin- 7-yl)-2- fluorobenzonitrile hydrochloride::US20240216357, Example 133

SMILES NC1CCN(CC1)c1nc(-c2ccc(C#N)c(F)c2)c(-c2ccc(OC(F)(F)F)c(O)c2)c2nccn12

InChI Key InChIKey=CHIKZYIDDLWDGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 683180   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683180(US20240216357, Example 133 | 4-(5-(4- aminopiperid...)
Affinity DataIC50: 0.540nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683180(US20240216357, Example 133 | 4-(5-(4- aminopiperid...)
Affinity DataIC50: 7.17E+3nMAssay Description:A manual patch-clamp technology is used to evaluate whether the test compound has a potential inhibitory effect on a voltage-gated potassium ion chan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent