BDBM683200 4-(5-(4- aminopiperidin- 1-yl)-8-(3- hydroxy-4- (trifluoromethyl) phenyl)imidazolo [1,2-c]pyrimidin- 7-yl)-2- fluorobenzonitrile carboxylate::US20240216357, Example 154

SMILES NC1CCN(CC1)c1nc(-c2ccc(C#N)c(F)c2)c(-c2ccc(c(O)c2)C(F)(F)F)c2nccn12

InChI Key InChIKey=YQYWLWPTLJFZEP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683200   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683200(US20240216357, Example 154 | 4-(5-(4- aminopiperid...)
Affinity DataIC50: 0.5nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
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Date in BDB:
10/11/2024
Entry Details
US Patent