BDBM683201 4-(5-(3-amino-8- azadicyclo[3.2.1] octane-8-yl)-8-(3- hydroxy-4- methoxyphenyl) imidazolo[1,2-c] pyrimidin-7-yl)-2- fluorobenzonitrile hydrochloride::US20240216357, Example 155

SMILES COc1ccc(cc1O)-c1c(nc(N2C3CCC2CC(N)C3)n2ccnc12)-c1ccc(C#N)c(F)c1

InChI Key InChIKey=ICWUWRPLRKHZJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 683201   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683201(US20240216357, Example 155 | 4-(5-(3-amino-8- azad...)
Affinity DataIC50: 0.200nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683201(US20240216357, Example 155 | 4-(5-(3-amino-8- azad...)
Affinity DataIC50: 1.80E+4nMAssay Description:Using mixed human liver microsomes as a CYP 450 enzyme source, specific probe substrates of respective CYP isoenzymes (2 substrates for CYP 3A4) are ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent