BDBM683234 4-(1-(4-methylpiperazin- 1-yl)-6-(p-tolyl)pyrrolo [1,2-a]pyrazin-7-yl) benzonitrile::US20240216357, Example 190

SMILES CN1CCN(CC1)c1nccn2c(c(cc12)-c1ccc(cc1)C#N)-c1ccc(C)cc1

InChI Key InChIKey=DKWNYCZLGGRBRA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683234   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandPNGBDBM683234(US20240216357, Example 190 | 4-(1-(4-methylpiperaz...)
Affinity DataIC50: 0.331nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
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Date in BDB:
10/11/2024
Entry Details
US Patent