BDBM683252 4-(5-(3-amino-8-azabicyclo [3.2.1]octan-8-carbonyl)- 2-(6-fluoro-3-methyl benzo[d]isoxazol-7-yl) thiophen-3-yl)-2-fluoro- benzonitrile hydrochloride::US20240216357, Example 209

SMILES Cc1noc2c(-c3sc(cc3-c3ccc(C#N)c(F)c3)C(=O)N3C4CCC3CC(N)C4)c(F)ccc12

InChI Key InChIKey=NPTQRLVSVJTCCJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683252   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683252(US20240216357, Example 209 | 4-(5-(3-amino-8-azabi...)
Affinity DataIC50: 0.507nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
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Date in BDB:
10/11/2024
Entry Details
US Patent